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This narrows arteries, raises blood pressure, and causes damage to organs like the liver, heart, and pancreas
Beyond proteasomal targeting, non-canonical ubiquitin modifications, including K63-linked polyubiquitination, regulate signaling, endocytosis, kinase activity, and DNA damage responses, while mono- and multi-ubiquitination influence chromatin dynamics, DNA repair, and subcellular localization (Fig
Acta Psychologica 42 : 313329
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